Sonata sleep med reviews

Choosing the right Sleeping Pill - ambien, lunesta

Zaleplon was rapidly absorbed with a time to peak concentration (tmax) of approximately 1 hour and a terminal-phase elimination half-life (t1/2) of approximately 1 hour. Zaleplon does not accumulate with once-daily administration and its pharmacokinetics are dose proportional in the therapeutic range. Zaleplon is rapidly and almost completely absorbed following oral administration. Peak plasma concentrations are attained within approximately 1 hour after oral administration. Although zaleplon is well absorbed, its absolute bioavailability is approximately 30 because it undergoes significant presystemic metabolism. Distribution, zaleplon is a lipophilic compound with a volume of distribution of approximately.4 L/kg following intravenous (IV) administration, indicating substantial distribution into extravascular tissues.

The structural formula is shown below. Zaleplon is a white to off-white powder that is practically insoluble in water and sparingly soluble in alcohol or propylene glycol. Its partition coefficient in octanol/water is constant (log.23) over the assignment pH range of 1. Sonata capsules contain zaleplon as the active ingredient. Inactive ingredients consist of microcrystalline cellulose, pregelatinized starch, silicon dioxide, sodium lauryl sulfate, magnesium stearate, lactose, gelatin, and titanium dioxide, d c yellow 10, fd c blue 1, fd c green 3, and fd c yellow 5. Pharmacodynamics and Mechanism of Action, while sonata (zaleplon) is a hypnotic agent with a chemical structure unrelated to benzodiazepines, barbiturates, or other drugs with known hypnotic properties, it interacts with the gamma-aminobutyric acid-benzodiazepine (gaba-bz) receptor complex. Subunit modulation of the gaba-bz receptor chloride channel macromolecular complex is hypothesized to be responsible for some of the pharmacological properties of benzodiazepines, which include sedative, anxiolytic, muscle relaxant, and anticonvulsive effects in animal models. Other nonclinical studies have also shown that zaleplon binds selectively to the brain omega-1 receptor situated on the alpha subunit of the gabaa/chloride ion channel receptor complex and potentiates (tbps) binding. Studies of binding of zaleplon to recombinant gabaa receptors (α1β1γ2 omega-1 and α2β1γ2 omega-2) have shown that zaleplon has a low affinity for these receptors, with preferential binding to the omega-1 receptor. Pharmacokinetics, the pharmacokinetics of zaleplon have been investigated in more than 500 healthy subjects (young and elderly nursing mothers, and patients with hepatic disease or renal disease. In healthy subjects, the pharmacokinetic profile has been examined after single doses of up to 60 mg and once-daily administration at 15 mg and 30 mg for 10 days.

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Tell each of your health care providers about all medicines you use now and any medicine you start or stop using. Further information Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use sonata only for the indication prescribed. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Copyright Cerner Multum, Inc. Medical Disclaimer Next side Effects Add to my med List More about Sonata (zaleplon) Consumer resources Professional resources Related reviews treatment guides. Generic Name: zaleplon, dosage form: capsule, medically reviewed on november 1, 2016, show On This Page. View All, civ, rX only, description, zaleplon is a nonbenzodiazepine hypnotic from the pyrazolopyrimidine class. The chemical name of zaleplon is Its empirical formula is C17H15N5o, and its molecular weight is 305.34.

Sonata (zaleplon) Uses, dosage, side Effects

See also: Side effects (in more detail) Sonata dosing information Usual Adult Dose for Insomnia: 5 to 20 mg orally immediately before bedtime or after the patient has gone to bed and has experienced difficulty falling asleep. Doses above 20 mg have not been adequately evaluated and are not recommended. Usual Geriatric Dose for Insomnia: Elderly patients and debilitated patients appear to be more sensitive to the effects of hypnotics, and respond to 5 mg of zaleplon. Doses over 10 evernote mg are not recommended. What other drugs will affect Sonata? Taking Sonata with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before taking a sleeping pill, narcotic pain medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression, or seizures. Other drugs may interact with zaleplon, including prescription and over-the-counter medicines, vitamins, and herbal products.

Sonata side effects Sonata may cause a severe allergic reaction. Get emergency medical help if you have any signs of an allergic reaction : hives; difficult breathing; nausea and vomiting; swelling of your face, lips, tongue, or throat. Stop using Sonata and call your doctor at once if you have: aggression, agitation, changes in behavior; anxiety, nervous feeling, depression, confusion, hallucinations; bronchospasm (wheezing, chest tightness, trouble breathing thoughts of hurting yourself; or a light-headed feeling, like you might pass out. Common Sonata side effects may include: problems with memory or coordination; drowsiness, dizziness; numbness or tingling; headache; upset stomach, constipation; dry mouth; back pain, chest pain; joint or muscle pain; or mild itching or rash. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to fda at 1-800-fda-1088.

Sonata, review 1(6) by, sonata

sonata sleep med reviews

Sonata - the Truth About, sonata

Zaleplon is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription. See also: Dosage Information (in more detail what happens if I miss a dose? Since sonata is usually taken as needed, you may not be on a dosing schedule. Never take this medication if you do not have at least 4 hours to sleep before being active again. Do not take extra medicine to make up a missed dose. What happens if i overdose? Seek emergency medical attention or call the poison Help line.

Overdose symptoms may include severe drowsiness, confusion, loss of coordination, limp muscles, weak business or shallow breathing, fainting. What should i avoid? Dangerous side effects could occur. Do not take other medicines that make you sleepy (such as cold medicine, pain medication, muscle relaxants, and medicine for depression or anxiety). Avoid taking Sonata during travel, such as to sleep on an airplane. You may be awakened before the effects of the medication have worn off. Amnesia (forgetfulness) is more common if you do not get at least 4 hours of sleep after taking a dose.

Do not take sonata during your normal waking hours, unless you have at least 4 hours to dedicate to sleeping. Avoid taking Sonata within 1 hour after eating a high-fat or heavy meal. This will make it harder for your body to absorb the medication. Sonata is for short-term use only. Do not take it for longer than 2 weeks without your doctor's advice.


Call your doctor if your insomnia symptoms do not improve, or if they get worse after using Sonata for 7 to 10 nights in a row. Sonata may be habit-forming, even at regular doses. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Selling or giving away sonata to any other person is against the law. Do not stop using zaleplon suddenly after taking it over several days in a row, or you could have unpleasant withdrawal symptoms. Follow your doctor's instructions about tapering your dose. Store at room temperature away from moisture, heat, and light. Keep track of the amount of medicine used from each new bottle.

Sonata 5 (Zaleplon) Info, med

It is not known whether zaleplon passes into breast milk or if it could harm a nursing baby. You review should not breast-feed while using this medicine. The sedative effects of Sonata may be stronger in older adults. Dizziness or severe drowsiness can cause falls or other accidents. How should I take sonata? Take sonata exactly as it was prescribed for you. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. If this happens, stop taking Sonata and talk with your doctor about another treatment for your sleep disorder.

sonata sleep med reviews

Sonata may be habit-forming. Keep the medication in a place where others cannot get. Misuse of this medication can cause addiction or overdose, especially in a child or other person using the medicine without a prescription. Selling or giving away sonata is against the law. Before taking this medicine, you should not use sonata if you are allergic to zaleplon. To make sure zaleplon is safe for you, tell your doctor if you have: liver or kidney disease; sleep apnea (breathing stops while you are asleep lung disease (asthma, bronchitis, emphysema, copd) or other breathing problems; a history of depression, mental illness, or suicidal thoughts;. It is not known whether zaleplon will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get. You may have withdrawal symptoms if you stop taking this medication after taking it over several days in a row. Do not stop taking Sonata suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely. To make sure this medicine is safe for you, tell your doctor if you have ever been addicted to drugs or alcohol.

Sonata will make you fall asleep. Never take this medication during your normal waking hours, unless you have at least 4 hours to dedicate to sleeping. Some people using this medicine have engaged in activity such as driving, eating, or making phone calls and later having no memory of the activity. If this happens to you, stop taking this medication and talk with your doctor about another treatment for your sleep disorder. Sonata can cause side effects that may oliver impair your thinking or reactions. You may still feel sleepy the morning after taking the medication. Until you know how this medication will affect you during waking hours, be careful if you drive, operate machinery, pilot an airplane, or do anything that requires you to be awake and alert.

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Generic Name: zaleplon (zah le plon brand Names: Sonata, medically reviewed on September 19, 2016, what is Sonata? Sonata (zaleplon) is a sedative, also called a hypnotic. It affects chemicals in your brain that may be unbalanced in people with sleep problems (insomnia). Sonata is used to treat insomnia. This medicine causes relaxation to help you tree fall asleep and stay asleep. Sonata may also be used for purposes not listed in this medication guide. Sonata may cause a severe allergic reaction. Stop taking Sonata and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.


sonata sleep med reviews
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  4. You should not use the information on this website for diagnosing or treating a medical or health condition on your own. Hypnotic (from Greek hypnos, sleep) or soporific drugs, commonly known as sleeping pills, are a class of psychoactive drugs whose primary function is to induce sleep and to be used in the treatment of insomnia (sleeplessness or surgical anesthesia).

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  7. Sonata (zaleplon) is a sedative, also called a hypnotic. It affects chemicals in your brain that may be unbalanced in people with sleep problems (insomnia). Sonata official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more.

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